Case study

Bespoke Fume Cupboard

Containment of solvent dispensing activities and solvent processing OSD equipment

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Challenge

Our client required two bespoke walk in fume cupboards including concealed HEPA filtration and specialist services as part of a new non-GMP pilot plant.

The intention of the plant is to support other GMP manufacturing facilities by providing a space to replicate and troubleshoot supply issues those plants are having in a non-GMP environment.

The Fume Cupboard required:

  • Stainless Steel for both internal and external components.
  • A precise 2.7m internal and 3.0m external wide radius profile.
  • The external environment needs to remain non-hazardous.
  • Incorporation of integral safety features to the Fume Cupboard.

These requirements posed significant challenges in terms of design precision, material handling, and integration of multiple features within a safety-critical environment.

Solution

To address these challenges, the project team at Howorth Air Technology implemented the following solutions:

  • Advanced fabrication techniques to achieve precise dimensions and a wide radius profile.
  • Engaged safety engineers to ensure the design met Class 1, Div. 2 standards for the internal environment.
  • Designed the external components to be non-hazardous, ensuring user safety.
  • Integrated safety features like LED lighting and a sprinkler cut-out without compromising the structural integrity of the hood.
  • Implemented modular design principles to incorporate the portable worktop and control system seamlessly.
  • 304L stainless steel safechange filter housing including Pre Filter and H14 HEPA filter

Outcome

The fume cupboard passed the static Factory Acceptance Test (FAT) without issues. Established a benchmark for future fume cupboard designs in terms of safety, functionality, and documentation.

Strengthened Howorth Air Technology's reputation in bespoke high-quality equipment manufacturing.

Following completion of the first model the Fume Cupboard was shipped to the US and a successful SAT test was carried out at the client’s factory.

The project successfully met all specified requirements and objectives and this facility will successfully provide a space for experimentation of new processes, products and technology.

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