Aseptic & Sterility Isolators
Aseptic Isolators are routinely found within the pharmaceutical industry and are widely used for a number of applications including:
- Sterility testing
- Sterile injectables
- Pharmacy dispensing
- Liquid filling
- Aseptic transfer
- Medical device manufacture and assembly
- Integration of key monitoring, processing and decontamination systems
Operators pose the greatest risk to product contamination during ‘conventional cleanroom’ aseptic processing.
Many different barriers of varying capabilities have been used to separate operators from critical sites during aseptic processing with the objective of reducing the probability of a contaminated unit.
These range from simple flexible curtains used on many traditional aseptic processing lines to
advanced aseptic processing in isolators.
A Restricted Access Barrier System (RABS) is an advanced aseptic processing system that can be utilised in many applications in fill-finish and processing areas.
RABS provides an enclosed environment to reduce the risk of contamination to product, containers, closures, and product contact surfaces compared to the risks associated with conventional cleanroom operations.
RABS can operate as “doors closed” for processing with very low risk of contamination similar to isolators or permit rare “open door interventions” provided appropriate measures are taken.
Uni-Directional Air Flow (UDAF) Booths and Canopies provide a localised clean air environment of ISO 5 (Grade ‘A’) over an aseptic process. They are usually positioned above machines and pieces of equipment within cleanrooms or secure environments.
The booths and canopies are of a customized design and built in modules or enclosures that can be standalone or integrated as part of the cleanroom facility.
Download our Pharmaceutical brochure
If you want to find out more, download our brochure or get in touch.
What our clients have to say
I wanted to let you know that Sam did a great job. We were really pleased with his professionalism and hard work. He didn't stop and was really knowledgeable when he went through the work sheets at the end of the job. We'd be really pleased to see him attend site again in the future
Thank you both for acting on our behalf with Mettler Toledo, you provided us with an efficient and effective service as always
Our interactions with Howorth have been excellent. The relationship has allowed us to establish our microbiological containment immunological analysis suite. The people I have worked with have been nothing but hepful, professional and capable. Design has been a partnership and the build quality has turned heads with some of my colleagues. In short, thank you Howorth.